Membrane Vesicles as Drug Delivery Systems: Source, Preparation, Modification, Drug Loading, In Vivo Administration and Biodistribution, and Application in Various Diseases

نویسندگان

چکیده

Bioinspired (or biologically inspired) drug delivery systems (DDSs) have been intensively studied in the last decades. As bioinspired DDSs, membrane vesicles, including extracellular vesicles (EVs) released from eukaryotic cells, outer (OMVs) bacteria, cell-bound (CBMVs) isolated situ cell surfaces, reorganized after isolation of plasma and others rapidly developed are attracting more attention. Most recently, a collection 25 papers on advances vesicle-based was published Special Issue Pharmaceutics entitled “Advances systems”. These cover many related topics source, preparation, modification, loading, vivo administration biodistribution (mainly or exosomes bacterial vesicles), as well application DDSs treatment various diseases.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Niosomes from Preparation to Application in Drug Delivery

Introduction: In recent years, the treatment strategy for infectious and autoimmune diseases has significantly changed. Up to now, cancer treatment has been conducted on the basis of clinical and pathological methods. The most common cancer treatments is limited to chemotherapy, radiation therapy and surgery. However, cancer treatment is still not optimal. Common challenges for treatment of cer...

متن کامل

Biological Application of Layered Double Hydroxides in Drug Delivery Systems

This review focuses on the extensive study of different layered double hydroxides (LDHs)nanostructures and also their biological and physicochemical (in vitro) properties to encapsulateand deliver drugs with a recognized pharmacokinetic profile in a sustained/modified manner forbetter remedial efficacy contrasted to the corresponding conventional treatments using different<br ...

متن کامل

In vivo evaluation of the biodistribution and safety of PLGA nanoparticles as drug delivery systems.

UNLABELLED The remarkable physicochemical properties of particles in the nanometer range have been proven to address many challenges in the field of science. However, the possible toxic effects of these particles have raised some concerns. The aim of this article is to evaluate the effects of poly(lactide-co-glycolide) (PLGA) nanoparticles in vitro and in vivo compared to industrial nanoparticl...

متن کامل

Drug delivery application of extracellular vesicles; insight into production, drug loading, targeting, and pharmacokinetics

Extracellular vesicles (EVs) are secreted from any types of cells and shuttle between donor cells and recipient cells. Since EVs deliver their cargos such as proteins, nucleic acids, and other molecules for intercellular communication, they are considered as novel mode of drug delivery vesicles. EVs possess advantages such as inherent targeting ability and non-toxicity over conventional nanocar...

متن کامل

Application of Various Types of Liposomes in Drug Delivery Systems

Liposomes, due to their various forms, require further exploration. These structures can deliver both hydrophilic and hydrophobic drugs for cancer, antibacterial, antifungal, immunomodulation, diagnostics, ophtalmica, vaccines, enzymes and genetic elements. Preparation of liposomes results in different properties for these systems. In addition, based on preparation methods, liposomes types can ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Pharmaceutics

سال: 2023

ISSN: ['1999-4923']

DOI: https://doi.org/10.3390/pharmaceutics15071903